Weight loss is a topic on everyone’s mind, and injectable medicines like Ozempic, Wegovy, and Mounjaro are creating a lot of buzz. But do they really help people shed pounds and keep them off? And are they safe? Dr Saptarshi Bhattacharya, an endocrinologist at Indraprastha Apollo Hospitals in Delhi, explains what you need to know.
As reported by HT, Dr Bhattacharya says, “These anti-obesity injections have been hailed as groundbreaking solutions. For some people, they provide hope after years of struggling with weight. But even as their popularity grows, legal controversies and questions about safety loom large.”
In the US, companies face lawsuits claiming they downplayed serious side effects, which makes medical guidance very important.
How Well Do These Weight Loss Injections Work?
Studies show these medicines can deliver strong results. Semaglutide, sold as Ozempic and Wegovy, helped people lose an average of 17 percent of their body weight over 68 weeks. About one-third of participants lost more than 20 percent. Tirzepatide (or Mounjaro) showed similar results, with many people losing over 20 percent on higher doses.
Dr Bhattacharya adds, “These drugs do more than just shed kilos. “They improve blood sugar, blood pressure, cholesterol, and reduce inflammation. Semaglutide also lowers the risk of serious heart problems. They can even help with obesity-related conditions, like sleep apnea and fatty liver disease.”
Possible Side Effects
Weight loss injections can cause side effects, especially in the gut. Nausea affects up to 44 percent of semaglutide users. Diarrhoea, vomiting and constipation are also common. Most problems are mild and fade over time. Doctors usually start with low doses and increase gradually to reduce discomfort.
Rare but serious risks exist, like pancreatitis, gut blockages, or a vision issue called NAION, which can cause sudden vision loss. Large studies show the risk of pancreatitis is very low, similar to placebo. Eye problems are extremely rare, but any sudden change in vision should be treated seriously.
Popularity And Caution When Using These Weight Loss Drugs
GLP-1 drugs like semaglutide are now the most widely used anti-obesity medicines in history, with millions using them worldwide. Still, more than 2,600 lawsuits are ongoing in the US over alleged side effects.
Dr Bhattacharya says.“Weight loss injections can be life-changing for those who struggle despite diet and exercise. But patients must understand the risks and watch for warning signs. With the right guidance, these medicines can help people lose weight safely and improve overall health.”
